Chemistry Questions
Explore questions in the Chemistry category that you can ask Spark.E!
Insoluble salts of a penicillin are used in what formulations?
Which PBP of staphylococci is sensitive to methicillin?
An electron withdrawing group in a cephalosporin (where the leaving group might be) increases what kind of activity?
What type of adverse effect/side effect is described by: - cell mediated hypersensitivity that is mediated by T lymphocytes
What specific type of beta - lactamase uses metals to open up the beta - lactam ring?
What type of adverse effect/side effect is described by: - immune complexes, serum sickness - like reactions and drug fever
Are ethers considered EWG or EDG?
What is the primary indication for the use of the fifth generation cephalosporin?
What specific type of beta - lactamases go after 3rd generation cephalosporins and carbapenems?
What is the only 5th generation cephalosporin that is on the market for clinical use?
What kind of coverage does ceftolozane have when given as a combination drug with tazobactam?
What are the two most common irreversible beta - lactamase inhibitors?
What is the renal function cutoff that we should start thinking about making dosing modifications?
Most beta - lactams are also actively secreted into ___________ by a saturable system
What substitution does 3rd generation cephalosporins have that make them unique?
Distribution: - ____________ distribution to most areas of the body but __________ penetrates mammalian cells- very high concentrations are found in __________ - penetration into the _________ is negligible unless inflammation is present because inflammation alters the _______ pump that removes beta - lactams from CSF - ________ protein binding - beta - lactams (do/do not) cross the placenta well
Are halogens considered EWG or EDG?
What medication can be given as an IM injection for meningitis?
What kind of coverage does ceftazidime have when given as a combination drug with avibactam?
Extra low affinity for ___________ by staphylococci produces methicillin resistance (MRSA)