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キニョンは、エンジェルアイランドの医務検査官として、プラークの発見や感染のテストなど、ペストの診断と制御に関与しました。また、サンフランシスコの保健委員会がチャイナタウンを封鎖した際には、その措置を支持しました。キニョンの実験室で行われたテストによって、ペストの原因であるYersinia Pestis(ヤーシニア・ペスチス)が確認されたことを指しています。つまり、実験室の検査結果により、ペストの感染が確認されたことを示しています。

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