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The blink reflex can be affected by anaesthetics. Local anaesthetics are used to stop peoplefeeling pain but do not make them unconscious. General anaesthetics make people unconsciousand stop them feeling pain.Doctors investigated two ways of measuring the effect of general anaesthetics.They gave:• anaesthetic S to 18 people• anaesthetic Q to 29 peopleThey recorded how long it took for the people to stop blinking.The doctors then repeated the investigation. This time, they used a machine that measures brainactivity to decide when a person was unconscious, rather than when blinking stopped. For eachperson, they recorded how long it took for the machine's readings to show that the person wasunconscious.Their results are shown in the table. A value of ±2 × SD from the mean includes over 95% of thedata.Blinking involves cholinergic synapses. Anaesthetic S is a similar shape to acetylcholine.Suggest how anaesthetic S stops the transmission across the synapse.

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