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Quelle est la proposition exacte ?Concernant les récepteurs à activité tyrosine kinase intrinsèque : A. Leur activité enzymatique entraine l'activation de la protéine RAS par phosphorylation du GDP en GTP.B. Leur activité enzymatique est activée par des ligands qui pénètrent dans la cellule.C. La phosphorylation des tyrosines de la partie intracellulaire du récepteur permet le recrutement de protéines adaptatrices à domaine SH2 impliquées dans la transmission du signal.D. Une fois activée, la protéine RAS est libérée dans le cytosol pour déclencher une cascade de réactions de phosphorylation.

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