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Penalties imposed by the inquisition for those found guilty of heresy

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"Their Highnesses can see that I will give them however much gold they need with what little aid they give me now: spices and cotton as much as they call for . . . and slaves as many as they order to be shipped. . . .Therefore, since our Redeemer has given this victory to our illustrious King and Queen and to their famously successful reigns, all Christians should rejoice, hold grand celebrations, and with solemn prayers give thanks to the Holy Trinity for the exaltation of turning so many peoples to our Holy Faith."-Source: Christopher Columbus, Letter to Luis de Santangel, Official Notary for King Ferdinand and Queen Isabella of Spain, 1493A historian would most likely use this passage to illustrate which of the following?
a. The trend shown is a representation of the Great Migration, where many African Americans left the Jim Crow South for the less discriminatory North/West. All of the places with large population loss are in the South and all of the states with large population gain are in the North/West (excluding Florida).b. One factor that led to the trend above was the wartime demand for industrial workers caused by WW1, encouraging many southern African Americans to migrate to northern cities for work. Another factor is the lesser discrimination in the North.c. One effect of the trend above is the Harlem Renaissance, where Harlem became the center of African-American literary, artistic, and political expression that was only made possible because of the large movement of African Americans to New York City.
hormones and paracrine can have __________ as means of providing negative feedback

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