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Name: Oseltamivir (Tamiflu) remember Tammy Swanson from Parks and Rec? MOA: Competitive Neuramidase inhibitor (earrings). Inhibition of NA prevents release of viral progeny from infected cells. Clinical: Treat and prevent influenza A and B infections (necklaces- the green thing is to symbolize prophylaxis) AE: Nausea, abdominal discomfort, emesis (she clutches her stomach). Prevented by taking with food (cereal bowl). Headaches (red lines by head). Psychiatric syndromes (remember that Tammy was crazy), renal syndromes (kidney on her sleeve). ADME: oral administration (cereal bowl, GI side effects). Renal clearance requires dose reduction in kidney failure (kidney on the sleeve with arrow)
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