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● Les radiations ionisantes à doses élevées altèrent les tissus.● La radiomucite chronique, secondaire à une irradiation cervico-faciale, présente à long terme un risque de transformation.● Ce risque est majoré par la présence d’autres facteurs carcinogènes (intoxication éthylo-tabagique persistante, état post-lichénien, la présence répétitive de rayons sur ces zones).● C’est une production plus importante de kératine qui cherche au départ à protéger la muqueuse. Cela ne se détache pas au passage de la sonde.Moins vrai aujourd’hui, car les champs d’irradiation sont beaucoup plus ciblés, et on protège les tissus périphériques.

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