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Evaluate the statements below, and select those that correctly apply to the characteristics of infection by herpes simplex virus.A. Initial infection with HSV-2 may be completely asymptomatic or may present with very painful vesicles and flu-like symptoms.B. Acyclovir and its derivatives can be taken either in pill form or topical and are a highly effective cure for herpes.C. HSV causing genital herpes enters a period of latency in the ganglion of the lumbosacral spinal nerve trunk where microRNAs are thought to regulate transcription of the viral genomeD. Transmission of HSV to a fetus or neonate is much more serious than transmission to an adult since it can enter the nervous system where it has a high mortality rate.E. HSV causing genital herpes enters a period of latency in the trigeminal nerve where microRNAs are thought to regulate transcription of the viral genome.

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