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En 30-årig kvinna söker för muskelsmärtor sedan ca 3 månader.Vid undersökning uppvisar hon dock ingen påtaglig muskelsvaghet, men man finner ett sänkt andningsljud och dämpning vid perkussion bilateralt över lungbaserna som vid pleuravätska, ett fynd som bekräftas vid lungröntgen.Laboratorieproverna visar ett positivt test för antinuklära antikroppar (ANA) och misstanke på njurpåverkan.Man gör en njurbiopsi där man påvisar inlagring av immunoglobulin och komplemetfaktor C1q i ett granulärt mönster i glomeruli.Vilken av följande immunologiska reaktionsmekanismer förklara bäst detta inlagringsmönster? (1p)a) Aktivering av IgE klädda mastcellerb) Inbindning av antikroppar riktade mot basalmembraner i glomeruli (kollagen IV)c) Antigen-antikroppskomplexbildningd) Makrofag-medierad frisättning av cytokinere) Frisättning av prostaglandiner
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