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Elle est suffisante pour différencier une tumeur bénigne d’une tumeur maligne. Elle est principalement pratiquée pour les tumeurs parotidiennes et les adénopathies. Elle peut être également utilisée pour les tumeurs profondes.La ponction-aspiration à l’aiguille est un geste simple qui peut être effectué sous contrôle radiologique ou échographie, mais ses indications restent limitées. Comme elle présente les inconvénients du prélèvement cytologique, on préfère en pratique la ponction-biopsie, excepté pour les lésions kystiques ou kysteuses

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