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Cytokine receptor patho Discuss the structures of the cytokine receptor and its associated JAK. What about thereceptor's structure prevents it from being on initially?o When a cytokine receptor binds its signal molecule, what happens to activate thereceptor?o When active how does the signal get sent to the nucleus? Discuss the role of the STATfamily of TF.o How is the path normally turned off by the cell?o A famous Finnish Winter Olympic family was found to have elevated RBC and was thusaccused of doping after winning several "gold medals". How did learning more about the erythropoietin path and the family flawed allele exonerate the family?

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