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Cytochrome c, a protein of the electron transport chain in the inner mitochondrial membrane, can be removed by relatively mild means, such as extraction with salt solution. In contrast, cytochrome oxidase from the same source can be removed only by extraction into detergent solutions or organic solvents. What kind of membrane proteins are cytochrome c and cytochrome oxidase? Explain. Draw a schematic diagram that shows how each protein is positioned in the membrane.
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