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A 75-year-old woman has been on a diuretic for many years to control her stage II hypertension. Her blood pressure at this visit is 165/80 mmHg. She is currently complaining of pain at her right hip and in both knees. She has increased her dose of ibuprofen (Motrin) from 400 mg three times daily (TID) to 800 mg TID. She is still in pain and would like something stronger. Which of the following is a true statement regarding the effects of ibuprofen (Motrin) on her disease?A. It increases the chances of adverse effects to her healthB. It inhibits the effect of renal prostaglandins and blunts the effectiveness of the diureticC. It prolongs the therapeutic effects of hydrochlorothiazide and other diureticsD. None of the statements are true

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