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A 4-year-old girl returns from a trip to Pakistan with her family. She develops a fever, headache, and abdominal pain that persists for one week. She has mild intermittent diarrhea, and a rash develops in the second week of the illness. Salmonella typhi is isolated from the blood that is ampicillin-resistant but chloramphenicol susceptible. Which of the following is the most common adverse effect that occurs with the use of chloramphenicol?

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Cholera is an acute infection of the digestive system that is caused by the bacterium Vibrio cholerae. Infected individuals can experience a range of symptoms, including diarrhea, vomiting, muscle cramps, low blood pressure, rapid heart rate, and extreme thirst. If symptoms persist and severe dehydration results, an infected individual can die within hours of symptom onset. The diagram below shows how cholera is transmitted.Based on the diagram, which of the following is the most likely reason that a community with good sanitation could still have individuals who contract cholera?A.) Disease transmission for cholera is through direct contact with infected individuals and is independent of sanitation conditions.B.) V. cholerae grow rapidly in clear, moving water that has limited nutrients or wastes.C.) Waste water treatment facilities that use high levels of chlorine to treat the outgoing municipal water supply have an increased risk of cholera outbreaks.D.) Runoff from a nearby agricultural field pollutes a reservoir used for drinking water.

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