Medicine Questions
Explore questions in the Medicine category that you can ask Spark.E!
For albumin list:1. the normal concentration in plasma2. the type of drug that binds to it3. an example
with most condition (renal failure, burns, trauma, etc) concentration of alpha acid glycoprotein willa. increaseb. decrease
T/F most drugs are not fully absorbed
Fentanyl (Sublimaze): Pregnancy Category
what does kinetic homogeneity state about the relationship between plasma drug concentration and concentration at the receptor site?
what are the 3 transport processes that drugs can be delivered/distributed?
what are two examples of uptake transporters?
higher Cmax = a. faster absorptionb. slower absorption
what organs have the highest perfusion of blood flow (therefore higher distribution)?
T/F orally disintegrating tablets bypass first pass metabolism
polar drugs display _______ absorption?a. the bestb. the poorest
which is better able to cross membranes?a. lipophilic drugsb. hydrophilic drugs
In what time frame do peak concentration usually occur?
what determines the half life of a drug:a. absorption b. elimination
Higher the AUC, the _____a. higher the bioavailabilityb. lower the bioavailability
what is one important determinant of intestinal permeability?
what is the transit time of a drug in the small intestine vs the large intestine?
what is the transit time of drug from the mouth to the anus?
what is the molecular weight at which permeability begins to decrease greatly?
identify whether the following medications increase of decrease transit time of gastric emptying:1. laxatives2. pain killers, opioids3. anticholinergics (benadryl)4. prokinetics (metaclopramide, erythromycin)5. glp-1 agonists (diabetes/weight loss meds)