Medicine Questions
Explore questions in the Medicine category that you can ask Spark.E!
What two groups of Sedative-Hypnotic drugs, exert inhibitory effects on polysynaptic reflexes and at high doses may also depress transmission at the skeletal neuromuscular junction?
Binding of what to BZ receptors facilitate /potentiate the inhibitory actions of GABA?
What is a selective anxiolytic, with minimal depressant effects on the CNS?
What stage of sleep is characterized by (70%-75% of sleep) N1, N2, N3 (deep or slow wave sleep)?
What is usually accompanied by some impairment of psychomotor functions and cognitive functions?
What type of GABA receptor is characterized by G protein coupled receptors and Activation causes K+ efllux
The steepness of the dose-response curve varies among drug groups. What can be determined by the flatness of the curve?
What does the CNS effects of most sedative-hypnotics depend on?
What promotes sleep onset and increase the duration of the sleep state?
What class of Sedative-Hypnotic Drugs inhibit complex I of electron transport chain?
What class of Sedative-Hypnotic Drugs may block the excitatory transmitter glutamic acid, and, at high concentration, sodium channels?
What sedative-hypnotic drugs exert calming effects with concomitant reduction of anxiety at relatively low doses?
What class does the anxiolytic drug belong to that interacts with the 5-hydroxytryptophan (5-HT1A) brain serotonin receptors as a partial agonist, but the precise mechanism of its anxiolytic effect is unknown?
Why is the dependence liability of zolpidem, zaleplon, and eszopiclone may be less than that of the benzodiazepines?
What type of BZ receptors mediate sedation?
What does not bind to BZ or GABA binding sites, but have their own site on the chloride ion channel?
What increase the frequency of GABA-mediated chloride ion channel opening.
Midazolam Oxazepam and Triazolam are benzodiazepines that have pharmacokinetics described as what?
What reverses the CNS effects of benzodiazepines and is classified as a competitive antagonist at BZ receptors.
What type of GABA receptor is characterized by Ionotropic receptors and Activation causes Cl- influx