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Relais des influx sensitifs des voies ascendantes provenant des récepteurs cutanés et propriocepteurs via le noyau cunéiforme et le noyau gracile. Il contient les noyaux viscéraux qui régissent la fréquence cardiaque, le diamètre des vaisseaux sanguins, le rythme respiratoire, le vomissement, la toux. C'est le site de la decussation des tractus corticospinaux ou pyramidaux
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