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Following ovulation, LH promotes the formation of the the corpus luteum. The corpus luteum secretes progesterone and some estrogen. Progesterone and estrogen maintain the thickened endometrium. Progesterone and estrogen inhibit the secretion of FSH and LH by the pituitary gland (negative feedback). If no embryo implants in the endometrium, the corpus luteum degenerates and no longer secretes progesterone and estrogen. This causes menstruation. FSH secretion is no longer inhibited and the cycle begins again.

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