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RÉCEPTEURS DE LA RYANODINE RYD2HOMOTÉTRAMÈRE:-large partie cytoplasmique N-terminale appelé « _____ »-4 segments transMBR en partie C-terminale dormant le pore du canal RyR2 en interaction avec des ___________ qui semblent participer à la régulation de son activité Canal du RyR2:-complexe macromoléculR (multiples interaction avec régions du pieds)-2 sites de fixations pour le Ca2+: -site haute affinité responsable de l'_________ du canal -site plus faible affinité= inactivation du canal -Canal ____________ du potentiel membranRDans la région du RyR2; site de fixation pour l'_________ qui active le canal du RyR2

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