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pi3k est recruté sur le recepteur --- au niveau de ces domaines ---, une fois les --- du recepteurs sont phosphorylées -> modification --- de la protéine -> activation --- de pi3k -> phosphorylation des --- membranaires qui servent comme --- ---. Les lipides = points d'--- pour --- et ---, au niveau des domaines --- -> changement conformationnel et activation de --- par pdk1

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