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both ____ and _____ signals are needed to get an adaptive immune response
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- 3 When antigen reaches a lymph node in a primed animal: A There is an increase in the output of cells in the efferent lymphatics over the following 24 h. B There is a decrease in the output of cells in the efferent lymphatics over the following 24 h. C There is an immediate output of activated blast cells. D It is transported to the spleen. E It is all immediately destroyed by macrophages.
- Directional selection is best described asall polymorphic alleles preserved in a populationT-cell receptor interaction with peptide:MHC complexes directed to a planar interfacea mechanism in T cells that is analogous to affinity maturation of immunoglobulinsselected alleles increase in frequency in a populationselection of most appropriate transplant donor directed at the identification of identical or similar combinations of HLA alleles compared with the transplant recipient.
- MHC class II molecules are made up of two chains called _______, whose function is to bind peptides and present them to _______ T cells:alpha (α) and beta (β); CD4alpha (α) and beta2-microglobulin (β2m); CD4alpha (α) and beta (β); CD8alpha (α) and beta2-microglobulin β2m); CD8alpha (α) and beta (β); γ:δ T cells.