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Lesch-Nyhan syndrome is an x-linked, rare, recessive disease caused by a mutation in the gene encoding for hypoxanthine-guanine phosphoribosyltransferase (HPRT1). A woman's maternal grandfather suffered from Lesch-Nyhan syndrome. She is concerned her male child could have Lesch-Nyhan syndrome. Genetically, what is the chance that this child has Lesch-Nyhan syndrome?
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