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In the first trimester, warfarin has fetotoxic effects, such as...
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- o Alcohol is associated with increased risk of spontaneous abortion. o Maternal alcohol intake affects the behaviours of the child, and this is how it is picked up as the facial features often go unnoticed o Attention span and lower academic ability often noted only at school o It can be difficult to establish alcohol as a cause, as there are often many other contributory factors o Damage to the brain is often, though not always accompanied by distinct facial deformities, physical and emotional developmental problems, memory and attention deficits, a variety of cognitive and behavioural problems o Affected individuals are at risk of developing a range of secondary comorbidities, including mental illness and alcohol and drug addiction o Facial dysmorphology includes: short palpebral fissures, a thin upper lip vermillion and a smooth philtrum